Michigan State played a home-and-home set last weekend with Bowling Green and the home team won each game.
Friday in Ohio, the Falcons took a 2-1 decision while MSU won 6-3 at home Saturday night.
Freshman Jim McKenzie scored the lone goal for the Spartans on Friday night and goalie Dominic Vicari stopped 24 shots.
"It's real frustrating, but it's the story of our season," said MSU forward Colton Fretter.
Saturday, sophomore Drew Miller had a four-point night with two goals and two assists. Vicari made 34 saves, including 17 in the third period. Fretter, McKenzie (seven goals in seven games), Ethan Graham and Bryan Lerg also scored. Senior captain Jim Slater notched three assists.
"Our performance was great tonight," said Spartans head coach Rick Comley. "We needed our big-time players to step up, and that is why I put Miller, Fretter and Slater together. Drew has had a great season. He went a little flat recently, probably from being tired, but he obviously played outstanding tonight. His goal to tie the game was huge."
The Spartans (15-15-4 overall, 10-13-3 CCHA) return to action for their final series of the regular season this weekend in a home-and-home series against Notre Dame. The teams will clash Friday in East Lansing at 7:05 and then travel to South Bend, Ind., Saturday for both teams' regular season finale.